Patent · US Expired

Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same

US6054127A · kind A · utility

6Cited by
16References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 27, 1997
Grant dateApr 25, 2000
Priority date
Expiry dateJun 27, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/6037
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo are disclosed. Methods of preparing the hapten-carrier conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.