Compounds and methods for the detection and prevention of T. cruzi infection
US6054135A · kind A · utility
7Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1997 |
| Grant date | Apr 25, 2000 |
| Priority date | — |
| Expiry date | Apr 15, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compounds and methods are provided for diagnosing Trypanosoma cruzi infection. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more epitopes of T. cruzi antigens. The compounds are useful in a variety of immunoassays for detecting T. cruzi infection. The polypeptide compounds are further useful in vaccines and pharmaceutical compositions for inducing protective immunity against Chagas' disease in individuals exposed to T. cruzi.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.