Patent · US Expired

Non-polar media for polynucleotide separations

US6056877A · kind A · utility

24Cited by
16References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 30, 1998
Grant dateMay 2, 2000
Priority date
Expiry dateOct 30, 2018

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01J20/287
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Nonporous beads having an average diameter of about 0.5-100 microns are suitable for chromatographic separation of mixtures of polynucleotides when the beads comprise a nonporous particle which are coated with a polymer or which have substantially all surface substrate groups endcapped with a non-polar hydrocarbon or substituted hydrocarbon group. The beads provide efficient separation of polynucleotides using Matched Ion Polynucleotide Chromatography.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.