Antimicrobial cationic peptides
US6057291A · kind A · utility
30Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1996 |
| Grant date | May 2, 2000 |
| Priority date | — |
| Expiry date | Dec 10, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH.sub.2 --KWKSFIKKLTTAVKKVLTTGLPALIS--COOH (SEQ ID NO:1) and NH.sub.2 --KWKSFIKKLTSAAKKVVTTAKPLISS--COOH (SEQ ID NO:2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.