Sigma receptor ligands and the use thereof
US6057371A · kind A · utility
149Cited by
6References
72Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 10, 1992 |
| Grant date | May 2, 2000 |
| Priority date | — |
| Expiry date | Jun 10, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to methods for the treatment of central nervous system disorders, gastrointestinal disorders, drug abuse, angina, migraine, hypertension and depression by administering a pharmaceutical composition comprising an effective amount of certain sigma receptor ligands to a patient in need of such treatment. The invention further relates to novel sigma receptor ligands having high binding to the sigma receptor and pharmaceutical compositions thereof. Unexpectedly, certain of the sigma receptor ligands of the present invention have selectivity for the sigma receptor over the DA, PCP and 5-HT.sub.1A receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.