Preparation process for .alpha., .beta.-dicarbonylated compounds
US6057474A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 1998 |
| Grant date | May 2, 2000 |
| Priority date | — |
| Expiry date | Dec 22, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C67/333
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Preparation process for .alpha.,.beta.-dicarbonylated compounds of formula (I) ##STR1## in which R.sub.2 =alkyl, phenyl or benzyl being able to be substituted in various ways on the cycle, or carboxylic ester, and R.sub.3 =alkyl or alkoxy or carboxylic ester in which a compound of formula (II) ##STR2## in which R.sub.1 =alkyl, or alkyl .alpha.-ketocarboxylate or carboxylic ester, and R.sub.2 and R.sub.3 have the same meanings as previously is reacted in a nitrile type solvent, with molecular oxygen in the presence of copper.sup.II nitrate or ferric chloride as catalyst, and use for obtaining ethyl .alpha.-ketobutyrate, ethyl phenyl pyruvate, ethyl pyruvate, ethyl phenylglyoxylate, butane-2,3-dione or diethyl mesoxalate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.