Patent · US Expired

Compositions that specifically bind to colorectal cancer cells and methods of using the same

US6060037A · kind A · utility

65Cited by
12References
10Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 26, 1996
Grant dateMay 9, 2000
Priority date
Expiry dateApr 26, 2016

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/245
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Conjugated compounds which comprise an ST receptor binding moiety and a radiostable active moiety are disclosed. Pharmaceutical compositions comprising conjugated compound which comprises an ST receptor binding moiety and a radiostable active moiety or an ST receptor binding moiety and a radioactive active moiety are disclosed. Methods of treating an individual suspected of suffering from metastasized colorectal cancer are disclosed. Methods of radioimaging metastasized colorectal cancer cells are disclosed. In vitro methods, kits and reagents are disclosed for determining whether or not an individual has metastasized colorectal cancer cells, for determining whether tumor cells are colorectal in origin and for analyzing tissue samples from the colon tissue to evaluate the extent of metastasis of colorectal tumor cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.