Multicistronic expression units and their use

US6060273A · kind A · utility

Assignees

• BEIERSDORF AG · DE
• Gesellschaft fur Biotechnologische Forschung mbH (GBF) · DE

Inventors

• Wilhelm Dirks · Braunschweig, DE
• Manfred Wirth · Leipzig, DE
• Hansjorg Hauser · Braunschweig, DE
• Wolfram Eichner · Rockenberg, DE
• Volker Achterberg · Hamburg, DE
• Albrecht Dorschner · Hamburg, DE
• Wolfgang Meyer-Ingold · Hamburg, DE
• Heiko Mielke · Neu Wulmstorf, DE

Key dates

• Filing date: Jun 2, 1997
• Grant date: May 9, 2000
• Expiry date: Jun 2, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2840/44
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Multicistronic expression units allow the equimolar expression of the genes located in the corresponding cistrons. These expression units are particularly suitable for the recombinant production of proteins composed of two or more polypeptide subunits.