Process for synthesizing carbapenem side chain intermediates
US6060607A · kind A · utility
6Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 16, 1999 |
| Grant date | May 9, 2000 |
| Priority date | — |
| Expiry date | Jun 16, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/572
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process of synthesizing a compound of the formula 1: ##STR1## is described. A compound of the formula 2: ##STR2## is reacted with diphenylphosphinic chloride to activate the carboxylic acid group, and then reacted with methanesulfonyl chloride to produce a compound of formula 4: ##STR3## Compound 4 is then reacted with a group II metal sulfide source in water to produce a compound of formula 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.