Serotonin 5-HT6 receptor knockout mouse
US6060642A · kind A · utility
1Cited by
1References
3Claims
0Family size
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Key dates
| Filing date | Aug 11, 1998 |
| Grant date | May 9, 2000 |
| Priority date | — |
| Expiry date | Aug 11, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0356
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention features transgenic mice models for gene function, wherein the transgenic mice are characterized by having altered serotonin 5-HT6 receptor gene function. The transgenic mice may be either homozygous or heterozygous for a disruption in the endogenous 5-HT6 gene. Transgenic mice homozygous for a disruption in the endogenous 5-HT6 gene display a phenotype of increased anxiety behavior including diminished investigation of foreign objects and an elevation in stretched attend postures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.