Method for detecting and diagnosing disease caused by pathological protein aggregation
US6063636A · kind A · utility
1Cited by
1References
20Claims
0Family size
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Key dates
| Filing date | Jan 19, 1996 |
| Grant date | May 16, 2000 |
| Priority date | — |
| Expiry date | Jan 19, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8831
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method is provided for detecting pathological macromolecules in a patient, comprising obtaining body fluid from the patient, pretreating the body fluid, subjecting the pretreated body fluid to size-exclusion chromatography to create an excluded fluid, and analyzing the excluded fluid to detect macromolecules having a predetermined molecular weight. The method also allows for comparing elution spectra with reference spectra of suspect pathologic proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.