Patent · US Expired

Esters of (+)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidi nemethanol

US6063793A · kind A · utility

1Cited by
35References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 22, 1999
Grant dateMay 16, 2000
Priority date
Expiry dateJun 22, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D211/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is directed to esters of (+)-.alpha.-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidine methanol, pharmaceutical formulations, methods of making and methods of using these esters. These compounds antagonize the effects of serotonin at the 5HT.sub.2A receptor and are useful in treating various conditions such as, for example, psychoses such as schizophrenia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.