Placenta trophoblast-specific gene
US6063912A · kind A · utility
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6Claims
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Key dates
| Filing date | Aug 6, 1998 |
| Grant date | May 16, 2000 |
| Priority date | — |
| Expiry date | Aug 6, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4702
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Expression of the polynucleotide molecule, Psx, is restricted to placenta, and in particular, to placenta trophoblast cell layers during embryogenesis. The expression pattern of Psx is exploited to detect trophoblast specific lineages, such as labyrinthine trophoblast layer and giant cells. The invention provides an isolated DNA molecule encoding Psx protein, and chimeric constructs, vector and host cells containing the isolated DNA. Also provided is a method for identifying putative abortion-inducing agents, which may offer an alternative to surgical abortion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.