Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding
US6066459A · kind A · utility
108Cited by
3References
13Claims
0Family size
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Key dates
| Filing date | Jun 19, 1998 |
| Grant date | May 23, 2000 |
| Priority date | — |
| Expiry date | Jun 19, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6441
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A spectral imaging method for simultaneous detection of multiple fluorophores aimed at detecting and analyzing fluorescent in situ hybridizations employing numerous chromosome paints and/or loci specific probes each labeled with a different fluorophore or a combination of fluorophores for color karyotyping, and at multicolor chromosome banding, wherein each chromosome acquires a specifying banding pattern, which pattern is established using groups of chromosome fragments labeled with various fluorophore or combinations of fluorophores.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.