Morphological mutants of filamentous fungi
US6066493A · kind A · utility
13Cited by
7References
64Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 1997 |
| Grant date | May 23, 2000 |
| Priority date | — |
| Expiry date | Mar 13, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/77
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive hyphal branching than the parent cell; and (c) identifying the mutant cell which has an improved property for production of a heterologous polypeptide than the parent cell, when the mutant and parent cells are cultured under the same conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.