Metalloproteinase inhibitors
US6066633A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1998 |
| Grant date | May 23, 2000 |
| Priority date | — |
| Expiry date | Nov 13, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compound of formula (I): ##STR1## in which: m represents an integer from 1 to 4 inclusive, and n and p an integer from 0 to 4 inclusive, PA1 X represents O, S or a single bond, PA1 R.sub.1 represent hydrogen or halogen, or alkyl, alkoxy, hydroxy, trihaloalkyl or trihaloalkoxy, PA1 R.sub.2, R.sub.3 and R.sub.4, which may be same or different, each represents hydrogen or alkyl, PA1 R.sub.5 represents hydrogen or halogen, or alkoxy, aryloxy or heteroaryloxy, PA1 R.sub.6, R.sub.7 and R.sub.8, which may be same or different, each represents hydrogen or alkyl, or together form, with the atoms carrying them respectively, an optionally substituted heterocycle, PA1 R.sub.9 represents SO.sub.3 H, --CO.sub.2 R.sub.10, --CO--NR.sub.11 R.sub.12, or --NR.sub.13 R.sub.14, wherein R.sub.10, R.sub.11, R.sub.12, R.sub.13 and R.sub.14 each represents hydrogen or alkyl or together (R.sub.11 /R.sub.12 ; R.sub.13 /R.sub.14) form, with nitrogen carrying them, heterocycle, isomers thereof, and addition salts thereof with a pharmaceutically-acceptable acid or base.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.