Patent · US Expired

Nucleotide sequences and methods for detection of Serpulina hyodysenteriae

US6068843A · kind A · utility

4Cited by
21References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 2, 1997
Grant dateMay 30, 2000
Priority date
Expiry dateOct 2, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/20
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention provides a method for detecting the presence of Serpulina hyodysenteriae in a biological sample, an oligonucleotide primer and an S. hyodysenteriae-specific oligonucleotide probe useful in that method, and an article of manufacture that contains the primers and/or probe. Also provided are an about 2.3-kb DNA fragment derived from genomic DNA of S. hyodysenteriae and encoding for an about 56 kDa polypeptide, a recombinant expression vector containing the DNA fragment, the 56 kDa polypeptide and a monoclonal antibody reactive with the peptide, and a method of assaying for antibodies reactive with the 56 kDa peptide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.