Fused heterocyclic benzenecarboxamide derivatives and PGD.sub.2 antagonists comprising them
US6069166A · kind A · utility
1Cited by
7References
18Claims
0Family size
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Key dates
| Filing date | May 28, 1999 |
| Grant date | May 30, 2000 |
| Priority date | — |
| Expiry date | May 28, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/76
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound, pharmaceutically acceptable salt thereof, or hydrate thereof having a PGD.sub.2 -antagonistic activity, and an inhibitory activity against infiltration of eosinophils, useful for treating mast cell dysfunction-associated diseases, such as systemic mastocytosis and disorder of systemic mast cell activation, as well as tracheal contraction, asthma, allergic rhinitis, allergic conjunctivitis, urticaria, ischemic reperfusion injury, inflammation and atopic dermatitis, which is shown by the formula (I): ##STR1## is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.