Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
US6071915A · kind A · utility
1Cited by
5References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 8, 1998 |
| Grant date | Jun 6, 2000 |
| Priority date | — |
| Expiry date | May 8, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a series of arylsubstituted piperazines, of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the .alpha.-1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this and other disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.