Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same
US6071982A · kind A · utility
148Cited by
22References
30Claims
0Family size
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Key dates
| Filing date | Apr 18, 1997 |
| Grant date | Jun 6, 2000 |
| Priority date | — |
| Expiry date | Apr 18, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S525/903
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A bioerodible polymeric semi-IPN alloy which comprises a first bioerodible polymer capable of producing acidic products upon hydrolytic degradation; a second bioerodible polymer, which provides a biopolymeric scaffolding or internal reinforcement; and optionally a buffering compound that buffers the acidic products within a desired pH range. In a preferred embodiment, the second bioerodible polymer comprises polypropylene fumarate (PPF), which is cross-linked, desirably by a vinyl monomer such as vinyl pyrrolidone (VP) to form the biopolymeric scaffolding which provides the semi-IPN with dimensional and geometric stability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.