Modified chromatographic support materials

US6074555A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Karl-Siegfried Boos · Gauting, DE
• Andreas Walfort · Warburg, DE
• Friedhelm Eisenbeiss · Griesheim, DE
• Dieter Lubda · Bensheim, DE

Key dates

• Filing date: Apr 3, 1995
• Grant date: Jun 13, 2000
• Expiry date: Apr 3, 2015

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2220/54
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The invention relates to improved chromatographic support materials, to the preparation thereof and to the use thereof as sorbent for chromatography. The particles of these materials have hydrophobic surfaces consisting of fatty acid esters in the pores and hydrophilic outer surfaces. The materials according to the invention permit direct separation of protein-containing samples by means of reverse phase methods.