CDNA for human methylenetetrahydrofolate reductase
US6074821A · kind A · utility
5Cited by
0References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 12, 1997 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Feb 12, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a cDNA probe for human methylenetetrahydrofolate reductase (MTHFR), and its uses. The probe of the present invention may be used for the identification of sequence abnormalities in patients with severe or mild MTHFR deficiency, including cardiovascular patients and patients with neurologic symptoms. A human MTHFR protein which hybridizes to the probe of the present invention may be used for therapy of MTHFR-deficiency patients by biochemical or pharmacological approaches.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.