Cloning of perilipin proteins
US6074842A · kind A · utility
1Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 16, 1996 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Dec 16, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides isolated nucleic acid sequences, i.e., polynucleotides, which encode a family of perilipin proteins. The present invention also provides isolated, substantially purified perilipin proteins which are useful as markers for differentiating true adipocytes from non-adipocyte cells which, as a result of pathophysiological conditions, assume adipocyte characteristics and become lipid-laden. The present invention further provides methods for producing a substantially purified perilipin protein and methods for detecting the presence of such perilipin proteins in a biological samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.