Reagents for intracellular delivery of macromolecules
US6075012A · kind A · utility
71Cited by
5References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 11, 1994 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Feb 11, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/543
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses cationic lipids and lipophilic compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Also disclosed are compositions of cationic lipids and viral components or non-viral fusagenic compounds useful for enhancing transfection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.