6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6075016A · kind A · utility
3Cited by
114References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1997 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Apr 10, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram, with improved selectivity with regard to, e.g., PDE V inhibition. The present invention includes compounds of Formula I: ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.