Xanthine modulators of metabolism of cellular P-450
US6075029A · kind A · utility
8Cited by
11References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 2, 1998 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Jan 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A new class of xanthine compounds, variously substituted at the 1, 3, 7 and 8 positions, is characterized by an ability to modulate the activity of key enzymes involved in drug metabolism. These compounds generally are useful in affecting drug metabolism and, particularly, in extending the circulating half-life of compounds that are metabolized via P-450-mediated pathways.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.