Human antibodies derived from immunized xenomice
US6075181A · kind A · utility
995Cited by
8References
3Claims
0Family size
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Antibodies with fully human variable regions against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.