Thioureido-cyclodextrins, utilized in particular to solubilize anti-tumor, and antiparasitic agents and their preparation processes
US6080733A · kind A · utility
2Cited by
1References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 20, 1998 |
| Grant date | Jun 27, 2000 |
| Priority date | — |
| Expiry date | Oct 20, 2018 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to thioureido-cyclodextrins, usable in particular to solubilize anti-tumor and antiparasitic agents and their preparation processes. These thioureido-cyclodextrins correspond to the formula: ##STR1## with m=6, 7 or 8, R.sup.1 represents OH or NH--CS--NHR.sup.2, at least one of the R.sup.1 being NH--CS--NHR.sup.2, PA1 R.sup.2 represents an alkyl, monosaccharide, oligosaccharide glycosyl-amino acid or glycopeptide group. These cyclodextrins are usable for solubilizing anti-tumor or antiparasitic agents of the Taxol family.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.