Modulators of molecules with phosphotyrosine recognition units
US6080770A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 19, 1999 |
| Grant date | Jun 27, 2000 |
| Priority date | — |
| Expiry date | Feb 19, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/3882
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel organic compounds, to methods for their preparation, to compositions containing them, to their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their use in diagnosis. The invention relates to modulation of the activity of molecules with phospho-tyrosine recognition units, including protein tyrosine phosphatases (PTPases) and proteins with Src-homology-2 domains, in in vitro systems, microorganisms, eukaryotic cells, whole animals and human beings. The novel organic compounds are compounds of formula (I) ##STR1## wherein (L).sub.n, Ar.sub.1, R.sub.1 and A are as defined in the application.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.