Patent · US Expired

Methods for reducing the incidence of necrotizing enterocolitis

US6080787A · kind A · utility

51Cited by
9References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 3, 1997
Grant dateJun 27, 2000
Priority date
Expiry dateOct 3, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P1/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Enteral formulas that contain long-chain polyunsaturated fatty acids (PUFAs), as arachidonic acid (AA) and docosahexaenoic acid (DHA) that are essentially free of cholesterol, are described. More particularly, the invention relates to methods for reducing the incidence of necrotizing enterocolitis by administering compositions which provide .omega.-6 and .omega.-3 long chain PUFAs, phospholipids and/or choline. Compositions from egg yolk lipids are presently preferred as they contain .omega.-6 and .omega.-3 long chain PUFAs and are predominantly in a phosphtidylcholine form. This is believed to provide a synergistic effect.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.