Conformationally locked nucleosides and oligonucleotides
US6083482A · kind A · utility
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7Claims
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Key dates
| Filing date | May 11, 1999 |
| Grant date | Jul 4, 2000 |
| Priority date | — |
| Expiry date | May 11, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3231
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Conformationally restricted 3',5'-bridged nucleoside analogues are described herein. The compounds can be prepared by cyclization at C3' and C5' of nucleosides through a linker or linking molecule. The nucleoside bases may be modified or unmodified. The nucleosides can be used as oligonucleotide building blocks or as small molecule pharmaceutical ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.