Near infrared radiation in-vivo diagnostic methods and dyes

US6083485A · kind A · utility

Assignees

• Institut fur Diagnosikforschung GmbH · DE
• Der Freien Universitat Berline · DE

Inventors

• Kai Licha · Berlin, DE
• Bjorn Riefke · Berlin, DE
• Wolfhard Semmler · Glienicke, DE
• Ulrich Speck · Berlin, DE
• Christoph-Stephan Hilger · Berlin, DE

Key dates

• Filing date: Nov 7, 1997
• Grant date: Jul 4, 2000
• Expiry date: Nov 7, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09B69/105
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.