Patent · US Expired

System and method for solid-phase parallel synthesis of a combinatorial collection of compounds

US6083682A · kind A · utility

58Cited by
38References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 19, 1997
Grant dateJul 4, 2000
Priority date
Expiry dateDec 19, 2017

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides a system and method for synthesizing chemicals onto supports in a parallel manner to produce a combinatorial collection of compounds. The system includes a plurality of middle plates, with each middle plate defining a plurality of reaction zones arranged in a two dimensional array. The reaction zones are adapted to receive a solid support, such as a sheet of membrane, and the middle plates are stackable on each other to form a three dimensional array of reaction zones. The system also includes a pair of end plates, where the middle plates are located between the end plates, and where the end plates include an array of fluid guides corresponding to the array of reaction zones, to allow for selective routing of reagents through the reaction zones.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.