Cancer susceptibility mutations of BRCA1
US6083698A · kind A · utility
11Cited by
2References
91Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1997 |
| Grant date | Jul 4, 2000 |
| Priority date | — |
| Expiry date | Dec 11, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/912
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
New mutations have been found in the BRCA1 gene. The mutations are located at nucleotide numbers 421-2, 815, 903, 926, 1506, 2034, 2428, 3888, 3904, 4164, 4643, 5053, 5150, 5210, or 5396+40 of the gene sequence of BRCA1. A process for identifying a sequence variation in a BRCA1 polynucleotide sequence is disclosed. The identification process includes allele specific sequence-based assays of known sequence variations. The methods can be used for efficient, and accurate detection of a mutation in a test BRCA1 gene sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.