Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
US6083922A · kind A · utility
66Cited by
4References
20Claims
0Family size
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Key dates
| Filing date | Apr 2, 1997 |
| Grant date | Jul 4, 2000 |
| Priority date | — |
| Expiry date | Apr 2, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for treatment, prevention and containment of acute and chronic tuberculosis using a preservative-free concentrated tobramycin aerosol formulation delivering tobramycin to the lung endobronchial space including alveoli in an aerosol having mass medium average diameter predominantly between 1 to 5.mu.. The method comprises administration of tobramycin in concentration one to ten thousand times higher than the minimal inhibitory concentration of Mycobacterium tuberculosis. A method for containment of and decreasing infectivity periods of tuberculosis patients to shorter periods of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.