Agonist and antagonist antibodies to the chemokine receptor-2 (CCR2)
US6084075A · kind A · utility
41Cited by
2References
21Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Feb 28, 1997 |
| Grant date | Jul 4, 2000 |
| Priority date | — |
| Expiry date | Feb 28, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to antibodies which is capable of binding the monocyte chemoattractant protein 1 (MCP-1) receptor CCR2, especially those which are capable of acting either as an antagonist or agonist. The claimed antobodies can be used for in vitro and/or in vivo diagnostic, for screening and detection of tissues and classes of cells expressing the MCP-1 receptor, for screening for new drugs and for therapeutic use. The invention also relates to a preparation comprising the claimed antibody and a micro-organism or cell-line capable of producing the claimed antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.