Device and method for analyzing tumor cell invasion of an extracellular matrix
US6087157A · kind A · utility
65Cited by
13References
13Claims
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Key dates
| Filing date | Mar 25, 1997 |
| Grant date | Jul 11, 2000 |
| Priority date | — |
| Expiry date | Mar 25, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/915
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A device for analyzing the in-vitro growth properties of cells is disclosed. The device comprises an upper and lower chamber separated by a growth substrate interface comprising submucosa, preferably tunical submucosa, from a warm-blooded vertebrae. Methods for culturing eukaryotic cells and studying their growth characteristics, including the invasive growth characteristics of tumor cells, on the submucosal matrix are described.
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