Patent · US Expired

Cephalosporin antibiotics

US6087355A · kind A · utility

7Cited by
8References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 11, 1996
Grant dateJul 11, 2000
Priority date
Expiry dateOct 11, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention includes novel compounds of formula ##STR1## where A, B, D, and E are selected from the group consisting of carbon, nitrogen and sulfur, R.sup.99 is selected from the group consisting of sulfur, SO, SO.sub.2, NH, N-alkyl, oxygen, C.dbd.C (cis or trans), and C.tbd.C, and R.sup.12 is NR.sup.13 R.sup.14, ##STR2## The invention also includes the pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to .beta.-lactam antibiotics and are useful as antibacterial agents. The invention also relates to novel intermediates useful for making the novel compounds of the present invention and to novel methods for producing the novel compounds and intermediate compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.