Aryl-imidazolines and aryl-imidazoles useful as .alpha.-2 adrenergic agonists without cardiovascular side effects
US6087361A · kind A · utility
14Cited by
5References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 1997 |
| Grant date | Jul 11, 2000 |
| Priority date | — |
| Expiry date | Nov 17, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are disclosed for treating a mammal with a condition that responds to .alpha.2 agonist treatment without causing cardiovascular side effects using compounds of the formula ##STR1## wherein R.sub.1 is H, alkyl or 1 to 4 carbon atoms or a halogen atom, X is O or NH and A is H or an oxo group and wherein said compound does not cause a concomitant reduction in blood pressure of said mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.