Process for the preparation of an organ specific antibodies labeled with technetium-99m

US6090366A · kind A · utility

Assignee

• Cis Bio International · FR

Inventors

• Ludwig Kuhlmann · Flörsheim, DE
• Anton Mayer · Niedernhausen, DE

Key dates

• Filing date: Sep 1, 1998
• Grant date: Jul 18, 2000
• Expiry date: Sep 1, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2123/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process for the preparation of an organ-specific substance labeled with technetium-99m The invention relates to a process for the preparation of an organ-specific substance labeled with technetium-99m, in which no unwanted Tc-99m compounds are bound to the antibody. This is achieved by using the complexing agent required for the reducing agent in an amount which is stoichiometric relative to the reducing agent.