Cosmetic and pharmaceutical preparations comprising photostable UV filters

US6090374A · kind A · utility

Assignee

• BASF SE

Inventors

• Thorsten Habeck · Meckenheim, DE
• Sylke Haremza · Neckargemünd, DE
• Volker Schehlmann · Schifferstadt, DE
• Horst Westenfelder · Neustadt, DE
• Thomas Wunsch · Speyer, DE

Key dates

• Filing date: Oct 15, 1998
• Grant date: Jul 18, 2000
• Expiry date: Oct 15, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The use of substituted .alpha.-methylstyrene derivatives of the formula I, ##STR1## where the variables have the following meanings: R.sup.1 C.sub.4 -C.sub.10 -alkoxy, C.sub.1 -C.sub.12 -alkylamino, C.sub.1 -C.sub.12 -dialkylamino, substituents which confer solubility in water and which are selected from the group consisting of carboxylate, sulfonate or ammonium residues; PA0 R.sup.2 hydrogen, C.sub.2 -C.sub.10 -alkyl, C.sub.1 -C.sub.12 -alkoxy; PA0 R.sup.3 COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN; PA0 R.sup.4 COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN; where the substituents R.sup.3 and R.sup.4 are identical in each case; PA0 R.sup.5 and PA0 R.sup.6 independently of one another hydrogen, C.sub.1 -C.sub.12 -alkyl, C.sub.2 -C.sub.10 -alkenyl, C.sub.3 -C.sub.10 -cycloalkyl, C.sub.3 -C.sub.10 -cycloalkenyl, aryl, hetaryl, unsubstituted or substituted; as photostable UV filters in cosmetic and pharmaceutical preparations to protect the human skin or human hair from the sun's rays, alone or together with UV-absorbing compounds known per se for cosmetic and pharmaceutical preparations.