Substituted N-carboxyalkylpeptidyl derivatives as antidegenerative agents
US6090785A · kind A · utility
1Cited by
7References
21Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 15, 1992 |
| Grant date | Jul 18, 2000 |
| Priority date | — |
| Expiry date | Oct 15, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel N-carboxyalkylpeptidyl compounds represented by the formula ##STR1## which are found to be useful inhibitors of matrix metalloendoproteinases which degrade major components of articular cartilage and basement membranes causing degenerative diseases such as arthritis, periodontal disease, corneal ulceration and the like, and certain cancers, are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.