Miniaturized planar columns in novel support media for liquid phase analysis

US6093362A · kind A · utility

Assignee

• AGILENT TECHNOLOGIES, INC. · US

Inventors

• Patrick Kaltenbach · Bischweier, DE
• Sally A. Swedberg · Santa Cruz, US
• Klaus Witt · Keltern, DE
• Fritz Bek · Remchingen, DE
• Laurie S. Mittelstadt · Belmont, US

Key dates

• Filing date: Feb 11, 1999
• Grant date: Jul 25, 2000
• Expiry date: Feb 11, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T156/1064
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Miniaturized planar column devices are described for use in liquid phase analysis, the devices comprising microstructures fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the invention include associated laser-ablated features required for function, such as analyte detection means and fluid communication means. Miniaturized columns constructed under the invention find use in any analysis system performed on either small and/or macromolecular solutes in the liquid phase and may employ chromatographic, electrophoretic, electrochromatographic separation means, or any combination thereof.