Methods and compositions for use in gene therapy for treatment of hemophilia
US6093392A · kind A · utility
40Cited by
5References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 12, 1998 |
| Grant date | Jul 25, 2000 |
| Priority date | — |
| Expiry date | Mar 12, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14151
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention includes a composition comprising a recombinant adeno-associated viral vector comprising at least two adeno-associated virus inverted terminal repeats, a promoter/regulatory sequence, isolated DNA encoding Factor IX and accompanying 5' and 3' untranslated regions and a transcription termination signal, and methods of use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.