DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS

US6093539A · kind A · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Paul J. Maddon · Scarsdale, US
• Dan R. Littman · New York, US
• Leonard Chess · Scarsdale, US
• Richard Axel · New York, US
• Robin Weiss · London, GB
• J. Steven McDougal · Atlanta, US

Key dates

• Filing date: Jun 6, 1995
• Grant date: Jul 25, 2000
• Expiry date: Jun 6, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides an isolated single-stranded nucleic acid which encodes an aqueous-soluble polypeptide comprising at least a portion of a human T4 glycoprotein, which portion specifically forms a complex with a human immunodeficiency virus envelope glycoprotein.