Patent · US Expired

Amidino-camptothecin derivatives

US6093721A · kind A · utility

1Cited by
3References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 13, 1999
Grant dateJul 25, 2000
Priority date
Expiry dateMay 13, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A water soluble camptothecin derivative which is 20(S)-7-ethyl-9(N-methyl-N-phenyl)amidino-camptothecin and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them and a process for their preparation are described. The compound of the invention and its pharmaceutically acceptable salts are useful antitumor agents and are further charactcrised by having a remarkable therapeutic index.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.