4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents

US6093732A · kind A · utility

Assignee

• Pharmacia & Upjohn Company LLC · US

Inventors

• John Tucker · San Diego, US
• Valerie A. Vaillancourt · Portage, US
• Joseph Walter Strohbach · Mendon, US
• Karen Rene Romines · Durham, US
• Mark Edward Schnute · Kalamazoo, US
• Michele M. Cudahy · Kalamazoo, US
• Suvit Thaisrivongs · Kalamazoo, US
• Steven Ronald Turner · Kalamazoo, US

Key dates

• Filing date: Dec 1, 1998
• Grant date: Jul 25, 2000
• Expiry date: Dec 1, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides 4-hydroxyquinoline-3-carboxamide and hydrazide compounds of formula I ##STR1## These compounds are useful to treat or prevent the herpesviral infections, particularly, human cytomegaloviral infection.