Methods and composition for treating skin proliferative diseases
US6093745A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 25, 1997 |
| Grant date | Jul 25, 2000 |
| Priority date | — |
| Expiry date | Nov 25, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/155
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and a compositions are provided for treating a skin proliferation disease such as psoriasis to inhibit the proliferation of epidermal cells, particularly keratinocytes and to reduce the symptoms of erythematous scales associated with the disease. The method comprises administering to a mammalian host with a skin proliferation disease a composition comprising an effective amount of an aminoguanidine composition, generally in a pharmaceutically acceptable carrier. The invention also provides a composition comprising an aminoguanidine composition which can be formulated in a pharmaceutically acceptable carrier, in a topical application form or for oral administration. The composition finds use in alleviating symptoms associated with the disease, such as reducing size, thickness or scales of a psoriatic lesion, reducing erthema, decreasing itching and decreasing induration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.