Process for the continuous production of basic cyclic optically active .alpha.- amino acids

US6093823A · kind A · utility

Assignee

• Degussa AG · DE

Inventors

• Matthias Kottenhahn · Alzenau, DE
• Klaus Stingl · Alzenau, DE
• Karlheinz Drauz · Alzenau, DE

Key dates

• Filing date: Mar 24, 1998
• Grant date: Jul 25, 2000
• Expiry date: Mar 24, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D241/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention pertains to a process for the continuous production of basic cyclic optically active .alpha.-amino acids of general formula (I) by continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the residual amino acid or amino acid derivative in the mother liquid with the aid of an optically active acid.