Compositions containing thrombin and microfibrillar nanometer collagen, and methods for preparation and use thereof
US6096309A · kind A · utility
148Cited by
23References
66Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1998 |
| Grant date | Aug 1, 2000 |
| Priority date | — |
| Expiry date | Jun 17, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/04
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and microfibrillar collagen in an aqueous medium. In a preferred embodiment of the present invention, the compositions are used in a kit comprising two different components, one of which is autologous patient's plasma as the source of fibrinogen, and the other of which is the thrombin-containing composition which also contains microfibrillar collagen having an average diameter of about 3-30 nanometers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.